Cancer drugs

Cancer drugs

Drugs, agents used in the treatment of cancer or conditions related to cancer.

Industry: Pharmaceutical

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Cancer drugs

Sabarubicin

Pharmaceutical; Cancer drugs

A disaccharide analogue of the anthracycline antineoplastic antibiotic doxorubicin. Sabarubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and ...

DNA methyltransferase inhibitor SGI-110

Pharmaceutical; Cancer drugs

A dinucleotide antimetabolite of a decitabine linked via phosphodiester bond to a guanosine, with potential antineoplastic activity. Following metabolic activation by phosphorylation and ...

Volasertib

Pharmaceutical; Cancer drugs

A dihydropteridinone Polo-like kinase 1 (Plk1) inhibitor with potential antineoplastic activity. Volasertib selectively inhibits Plk1, inducing selective G2/M arrest followed by apoptosis in a ...

A difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the ...

Copper Cu 64 trastuzumab

Pharmaceutical; Cancer drugs

A diagnostic radioimmunoconjugate comprised of the recombinant humanised monoclonal antibody trastuzumab conjugated with the positron-emitting radioisotope copper Cu 64. Copper Cu 64 trastuzumab ...

Deuterated 3-methylhistidine

Pharmaceutical; Cancer drugs

A derivative of the amino acid histidine labelled with heavy hydrogen (D) used in diagnostic procedures. Upon intake of deuterated 3-methylhistidine (3-MH), this agent is incorporated into muscle ...

Gusperimus

Pharmaceutical; Cancer drugs

A derivative of the antitumor antibiotic spergualin with immunosuppressant activity. Gusperimus inhibits the interleukin-2-stimulated maturation of T cells to the S and G2/M phases and the ...