11 Terms
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Genome
Long-range restriction mapping
Biology; Genome
Restriction enzymes are proteins that cut DNA at precise locations. Restriction maps depict the chromosomal positions of restriction-enzyme cutting sites. These are used as biochemical "signposts," ...
Restriction enzyme, endonuclease
Biology; Genome
A protein that recognises specific, short nucleotide sequences and cuts DNA at those sites. Bacteria contain over 400 such enzymes that recognise and cut more than 100 different DNA sequences. See ...
Restriction fragment length polymorphism (RFLP)
Biology; Genome
Variation between individuals in DNA fragment sizes cut by specific restriction enzymes; polymorphic sequences that result in RFLPs are used as markers on both physical maps and genetic linkage maps. ...
Interference
Biology; Genome
One crossover event inhibits the chances of another crossover event. Also known as positive interference. Negative interference increases the chance of a second crossover. See also: crossing over.
Restriction-enzyme cutting site
Biology; Genome
A specific nucleotide sequence of DNA at which a particular restriction enzyme cuts the DNA. Some sites occur frequently in DNA (e.g., every several hundred base pairs); others much less frequently ...
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