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Genome

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Genome

Comparative genomics

Biology; Genome

The study of human genetics by comparisons with model organisms such as mice, the fruit fly, and the bacterium E. coli..

Single-gene disorder

Biology; Genome

Hereditary disorder caused by a mutant allele of a single gene (e.g., Duchenne muscular dystrophy, retinoblastoma, sickle cell disease). See also: polygenic disorders.

Metaphase

Biology; Genome

A stage in mitosis or meiosis during which the chromosomes are aligned along the equatorial plane of the cell..

Complementary sequence

Biology; Genome

Nucleic acid base sequence that can form a double-stranded structure with another DNA fragment by following base-pairing rules (A pairs with T and C with G). The complementary sequence to GTAC for ...

Megabase (Mb)

Biology; Genome

Unit of length for DNA fragments equal to 1 million nucleotides and roughly equal to 1 cM. See also: centimorgan.

Somatic cell

Biology; Genome

Any cell in the body except gametes and their precursors. See also: gamete.

Codominance

Biology; Genome

Situation in which two different alleles for a genetic trait are both expressed. See also: autosomal dominant, recessive gene.

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