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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
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Immunology
β2-microglobulin.
Biology; Immunology
The light chain of the MHC class I proteins is called β2-microglobulin. It binds noncovalently to the heavy or α chain.
Isotypic exclusion
Biology; Immunology
Isotypic exclusion describes the use of one or other of the light-chain isotypes, κ or λ, by a given B cell or antibody.
Polyspecificity
Biology; Immunology
Some antibodies show polyspecificity, the ability to bind to many different antigens. This is also known as polyreactivity.
Seroconversion
Biology; Immunology
Seroconversion is the phase of an infection when antibodies against the infecting agent are first detectable in the blood.
Recipient
Biology; Immunology
In any situation in which cells or tissues are transplanted, they come from a donor and are placed in a recipient or host.
Pathology
Biology; Immunology
Pathology is the scientific study of disease. The term pathology is also used to describe detectable damage to tissues.
Autoimmune response
Biology; Immunology
An adaptive immune response directed at self antigens is called an autoimmune response; likewise, adaptive immunity specific for self antigens is called autoimmunity.
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