Molecular biology

Molecular biology

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Molecular biology

Intermediary metabolism

Biology; Biochemistry

The individual enzymic reactions that in a tissue or inside a cell transform one metabolite into another, e.g. the conversion of lactate into glucose by the liver, the conversion of leucine into ...

Inhibitor of apoptosis (IAP) proteins are present in most animal cells and regulate the sensitivity of an animal cell to apoptosis-inducing stimuli by binding to and inhibiting activated caspases, ...

Right-handed helix

Biology; Biochemistry

By analogy with the right hand, a helix, e.g. of a polypeptide, that advances towards the C-terminus in the direction of the extended thumb as the backbone of a chain turns in the direction of the ...

Enhanceosome

Biology; Biochemistry

A highly-ordered cluster of tissue-specific transcription factors that assemble at regulatory elements of a eukaryotic gene and which, by their arrangement in space, act synergistically and ...

ATPase

Biology; Biochemistry

An enzyme that hydrolyses ATP; usually the partial activity of an enzyme, or system of enzymes, that uses the energy made available by the hydrolysis of ATP to drive an energetically unfavourable ...

Genotype

Biology; Biochemistry

The genetic composition of a cell or organism, usually with reference to a particular set of alleles that may be homozygous or heterozygous for a trait; the phenotype is the appearance of the cell or ...

BIAcore

Biology; Biochemistry

An optical instrument for detection of binding partners. A reflective surface is coated with a one of the pair, and is then exposed to a test solution. If binding occurs, the refractive index of the ...