R looping (R loops)

R looping (R loops)

A technique developed by M. Thomas, R. White, and R. Davis in which molecules of double-stranded DNA are incubated at temperatures below their denaturing temperature to open up short stretches of the DNA double helix so that single-stranded RNA molecules can begin to form DNA/RNA hybrids where the two are complementary. The DNA/RNA hybrid forms an R loop by displacing a single-stranded section of DNA.

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Part of Speech: noun
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Industry/Domain: Archaeology
Category: Human evolution
Company: ArchaeologyInfo.com
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