Colony hybridization

Colony hybridization

A technique for screening bacterial colonies for those that contain a desired polynucleotide sequence. A plate is exposed to a labelled oligonucleotide probe with a sequence complementary to part of the desired sequence which thus labels clones with that sequence. In a variant technique, plaque hybridization, phage vectors are screened for the desired polynucleotide sequence.

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Part of Speech: noun
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Industry/Domain: Biology
Category: Biochemistry; Molecular biology
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colony hybridization

Biotechnology; Genetic engineering

A technique that uses a nucleic acid probe to identify a bacterial colony with a vector carrying a specific cloned gene or genes.

colony hybridization

Biology; Biochemistry; Molecular biology

A technique for screening bacterial colonies for those that contain a desired polynucleotide sequence. A plate is exposed to a labelled oligonucleotide probe with a sequence ...

hybridization

Language; Translation & localization; Translation

Text types are rarely if ever pure. More than one text-type focus is normally discernible in a given text. This is known as hybridization.

hybridization

Natural environment; Coral reefs

The production of offspring (hybrids) from genetically dissimilar parents.

hybridization

Biotechnology; Genetic engineering

1. Interbreeding of species, races, varieties and so on, among plants or animals; a process of forming a hybrid by cross pollination of plants or by mating animals of different ...