Cosmid

Cosmid

Artificially constructed cloning vector containing the cos gene of phage lambda. Cosmids can be packaged in lambda phage particles for infection into E. coli; this permits cloning of larger DNA fragments (up to 45kb) than can be introduced into bacterial hosts in plasmid vectors.

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Part of Speech: noun
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Blossary:
Industry/Domain: Medical
Category: Human genome
Company: National Library of Medicine
Product:
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cosmid

Natural environment; Coral reefs

A DNA vector that allows the insertion of long fragments of DNA (up to 50 kbases).

cosmid

Biotechnology; Genetic engineering

A plasmid vector which contains the two cos (cohesive) ends of phage lambda (1) and one or more selectable markers such as an antibiotic resistance gene. Cosmids exploit certain ...

cosmid

Medical; Human genome

Artificially constructed cloning vector containing the cos gene of phage lambda. Cosmids can be packaged in lambda phage particles for infection into E. coli; this permits ...

cosmids

Archaeology; Human evolution

Cloning vectors derived from plasmids that are capable of cloning large fragments of DNA. In addition to the features of plasmid cloning vectors (i.e., origin or replication and ...

cosmid

Biology; Genome

Artificially constructed cloning vector containing the cos gene of phage lambda. Cosmids can be packaged in lambda phage particles for infection into E. coli; this permits cloning ...

cosmid

Medical; Health care; Medicine

Plasmids containing at least one cos (cohesive-end site) of phage lambda. They are used as cloning vehicles.

eugenics

Biology; Human genome

Eugenics is a bio-social movement which advocates the practice that very talented people should spread their genes by having more children, and less talented people should be ...

celiac disease

Medical; Human genome

A digestive disease that is caused by an immune response to a protein called gluten, which is found in wheat, rye, barley, and oats. Celiac disease damages the lining of the ...

atherosclerosis

Medical; Human genome

1) Age, lifestyle, diet, and gene related degeneration of arteries due to deposition of lipoid plaques (atheromas) on inner arterial walls; main cause of coronary artery disease, ...

astigmatism

Medical; Human genome

1) Unequal curvature of the refractive surfaces of the eye. Thus a point source of light cannot be brought to a point focus on the retina but is spread over a more or less ...

bone marrow transplantation

Medical; Human genome

The transference of bone marrow from one human or animal to another.

cavernous

Medical; Human genome

1) Having caverns or cavities. 2) Of tissue: composed largely of vascular sinuses and capable of dilating with blood to bring about the erection of a body part.