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Crossover experiment
A method to detect the control point in a metabolic pathway by observation of the effect on metabolite levels as new steady-state levels are established after sudden creation or relieving of an experimental deficiency in a controlling factor, e.g. the effect of oxygen on the redox state of reduced electron transport components, or the effect of oxygen on the levels of glycolytic intermediates of anaerobic tissue.
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- Part of Speech: noun
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- Industry/Domain: Biology
- Category: Biochemistry; Molecular biology
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