Biochemistry

Biochemistry

The scientific study of the chemistry of living matter.

Contributors in Biochemistry

Biochemistry

Descriptive of a mechanism of polymerization. The head of a biosynthetic monomer is defined as the chemically activated site (i.e. the carbonyl groups of amino acyl-tRNA or fatty acyl-CoA esters, the ...

Massively parallel signature sequencing (MPSS)

Biology; Biochemistry

A method for automated identification by sequence and quantitative evaluation of expressed genes, which is unaffected by sequence-dependent variations in hybridization efficiencies. A microbead cDNA ...

Bidirectional PCR amplification of specific alleles (bi-PASA)

Biology; Biochemistry

A method for determination of zygosity. Two sets of primers are used. Of the inner set, primer A is complementary to a point mutation on the coding strand and primer B is complementary to the ...

Amino acid

Biology; Biochemistry

Usually an α-amino acid, in which a carboxy and an amino (or imino) group are attached to the α-carbon; triple- and single-letter codes are shown: alanine Ala A arginine Arg R asparagine ...

Self-splicing

Biology; Biochemistry

The activity of the precursor of mature RNA whereby it catalyses its own (cis>) splicing. Group I introns (examples are Tetrahymena rRNA and hammerhead ribozymes) are self-spliced with the assistance ...

Mismatch repair analysis

Biology; Biochemistry

An assay system for detection of single-base mismatches in a DNA fragment of up to 10 Kb in length, which depends upon an Escherichia coli repair system that detects mismatched bases between a newly ...

Oncogene

Biology; Biochemistry

A gene present in normal cells which when altered can transform the normal cell into a malignant cell. (When emphasising this relationship, the unaltered gene is called a proto-oncogene and the ...