Biochemistry

Biochemistry

The scientific study of the chemistry of living matter.

Industry: Biology; Biotechnology

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Biochemistry

Technical knock-out approach (TKO)

Biology; Biochemistry

Used for the construction of apoptosis-incapable mutations. Use of a cytokine to induce apoptosis in the vast majority of cultured cells allows the survival of only those that have deficient ...

Transfer-messenger RNA (tmRNA)

A single or two-strand bacterial RNA with both tRNA and mRNA functions. As part of a ribonucleoprotein complex it can rescue a ribosome that has become trapped in a complex by a mRNA that has lost ...

Charge accumulator model

Biology; Biochemistry

A conceptualization of the mechanism of the water-splitting enzyme of photosynthesis in which four electrons are sequentially removed from the manganese center, enabling it to oxidise water to ...

Multiwire data collector

Biology; Biochemistry

A variety of area detector; an array of individual proportional photon detectors individually wired to a computer to allow quantification of energy and, in crystallographic experiments, its angle of ...

Contact site

Biology; Biochemistry

A small region where the mitochondrial inner and outer membranes touch, and at which structures exist that are responsible for transport of proteins and adenosine nucleotides into and out of the ...

Housecleaning enzyme

Biology; Biochemistry

An enzyme that hydrolyses or otherwise destroys a potentially mutagenic or physiologically disruptive metabolite; e.g. a nudix hydrolase, an enzyme that hydrolyzes a nucleoside diphosphatase-linked ...

Protein cage

Biology; Biochemistry

The reaction site within which inorganic materials are deposited and that can reach the supramolecular (i.e. nanometer) size, e.g. apoferritin, within which hydrated ferric oxide is deposited to form ...