Biochemistry

Biochemistry

The scientific study of the chemistry of living matter.

Contributors in Biochemistry

Biochemistry

A 10 to 200 nm protein-, cholesterol- and sphingolipid-rich microdomain of a membrane (e.g. plasma, endoplasmic reticulum, mitochondrial). These rafts are more ordered and thus denser than the lipid ...

Coincidence painting (chromosome painting)

Biology; Biochemistry

A method for production and utilisation of fluorophore-labelled oligonucleotides to identify very localised regions of chromosomes. The method of degenerate oligonucleotide primed PCR (DOP-PCR) ...

Double adaptor method

Biology; Biochemistry

CDNA concatamer sequencing; a method for increasing the efficiency of sequencing cDNA library subclones cDNA fragments are cleaved with a restriction nuclease and randomly religated into larger DNA ...

Vesosome

Biology; Biochemistry

An aggregate of smaller particles packaged into a larger membrane-bound structure. The aggregates are formed by attachment of biotin to individual liposomes or other small particles, then ...

SNARE hypothesis

Biology; Biochemistry

A proposal for the mechanism by which membranes, particularly vesicular and Golgi or plasma membranes, fuse during, for instance intracellular transport and secretion. The two membranes contain ...

Plectonemic

Biology; Biochemistry

Descriptive of the interaction of two DNA strands, either single- or double-stranded, in which an oligonucleotide of one strand is twisted into a plait of helices, one around the other, and requires ...

Colour PCR

Biology; Biochemistry

A technique for screening a population for a specific point mutation that uses fluorophore-labelled PCR primers. Three primers are designed for amplification of a restriction fragment that contains ...