Molecular biology

Molecular biology

Industry: Biology

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Molecular biology

Totipotency

Biology; Biochemistry

The capacity of a zygote to develop into a fully differentiated organism, a property lost as the zygote develops into more specialised cells that are more committed to particular lines of ...

Amphipathic helix

Biology; Biochemistry

A protein structure that serves in part as an interface between polar and non-polar phases; an a-helix that displays non-polar residues on one side and polar residues on the other (e.g. in many ...

Thin-layer chromatography (TLC)

Biology; Biochemistry

A technique to separate small molecules on a thin film of an adsorbent on a glass or semi-rigid plastic surface by their differential mobilities in a liquid phase that passes through the film by ...

An optical method for detection of the non-uniform dispersion of a macromolecule in solution, especially during analytical ultracentrifugation or free-zone electrophoresis, by the refractive index of ...

Hydrophobic zipping

Biology; Biochemistry

A view of the initiation of protein folding in which the formation of hydrophobic interactions between very close groups bring slightly more remote groups into interaction distance in an accelerating ...

Conservative mutation

Biology; Biochemistry

Such a mutation results in an amino acid substitution that preserves an essential chemical characteristic of the original, e.g. a leucine for an isoleucine, an aspartate for a glutamate, a lysine for ...

10Sa RNA

Biology; Biochemistry

A single or two-strand bacterial RNA with both tRNA and mRNA functions. As part of a ribonucleoprotein complex it can rescue a ribosome that has become trapped in a complex by a mRNA that has lost ...