8 Terms
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Molecular biology
Industry: Biology
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Molecular biology
Simple sequence DNA
Biology; Biochemistry
The highly repetitive non-coding DNA of a satellite that serves a structural role in mitosis; used for genetic characterization by its polymorphism (simple sequence length polymorphism, SSLP).
Molecular modelling
Biology; Biochemistry
Any of the computational approaches for relating chemical or physical properties to structure, e.g. design of agonists or antagonists from the X-ray crystallography data of a receptor protein.
Synzyme
Biology; Biochemistry
A synthetic enzyme, e.g. a polymer with an inert backbone, upon which dissociating groups like amines and carboxyls are mounted in a random fashion; or a protein product of in vitro evolution.
Excimer
Biology; Biochemistry
In fluorescence spectroscopy, a dimer of a fluorophore that is stable only in the excited state, e.g. of aromatics such as pyrene or 2,5-diphenyloxazole (PPO, used for scintillation counting).
Chromosomal map
Biology; Biochemistry
The localization of genetic traits to regions of chromosomes, by linkage studies (e.g. the association of haemophilia with the X chromosome) and by in situ hybridization to fluorescent probes.
Hemidesmosome
Biology; Biochemistry
A structure of the plasma membrane of an epithelial cell that extends into both the cytoplasm and the extracellular space, and anchors the cell to the extracellular matrix of the basal lamina.
Double duplex invasion
Biology; Biochemistry
A mechanism by which a pair of pseudocomplementary protein nucleic acids (PNAs) target and inactivate DNA. The DNA strands are unwound locallly and each is targeted simultaneously by one of the PNAs.
