Molecular biology

Molecular biology

Industry: Biology

Add a new term

Contributors in Molecular biology

Become a Contributors

Molecular biology

Loss-of-function

Biology; Biochemistry

Descriptive of a experimental biological model that is designed to be unable to express a particular trait; e.g. a cell line treated with an antisense oligodeoxynucleotide. This contrasts with a ...

Gene conversion

Biology; Biochemistry

The replacement of an allele during crossing- over owing to mismatch repair of the heteroduplex intermediate; rather than being equally represented in daughter DNA strands, one allele is ...

A hormone secreted by the pancreas that binds to its specific cell surface receptor in tissues throughout the body. Insulin regulates multiple growth and metabolic actions of cells including glucose ...

Transcription factor

Biology; Biochemistry

A protein that binds to a specific DNA sequence and enhances or suppresses transcription of the target gene. One class is the basic helix-loop-helix proteins; upon associating with another molecule ...

Hill plot

Biology; Biochemistry

A graphical representation of binding data, especially for oxygen binding to haemoglobin; a plot of log(Y/(1-Y)) against logpO 2 , where Y is the fraction of binding sites occupied and pO 2 is the ...

Centimorgan (cM)

Biology; Biochemistry

A genetic measure of the distance that separates markers in the same chromosome, especially in describing a map of the chromosome; the distance that permits a 1% frequency of crossing over (1 morgan ...

Triplet

Biology; Biochemistry

A three-base codon of the genetic code. Also a component of the mitotic spindle, seen in cross-section as one of nine structures, each composed of a microtubule doublet with an additional series of ...