Molecular biology

Molecular biology

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Molecular biology

Homology

Biology; Biochemistry

The similarity in base sequences of genes or amino acid sequences of proteins that denotes a common evolutionary origin; also the similarity of structure or function of proteins that is due to a ...

Picket fence porphyrin compound

A model oxygen-binding porphyrin in which bulky side chains on one face of the ring permit binding of molecular oxygen while preventing oxidation of Fe 2+ , which is co-ordinated on the other face of ...

Peptide Velcro

Biology; Biochemistry

A description of helix-helix interactions in which side chains of two parallel, adjacent helices closely interact due to complementary shapes and electrostatic interactions, e.g. the leucine zipper ...

Beta (β)-oxidation

Biology; Biochemistry

The series of enzymic reactions that oxidises fatty acyl-CoA esters and shortens them by removal of the C-terminal two carbon atoms as acetyl-CoA. More narrowly, it is the oxidation of a compound, ...

Signature sequence

Biology; Biochemistry

An insertion or deletion in the coding sequence of a gene which, because it is shared by phylogenetically distant species, is thought to be evolutionarily conserved and therefore can serve to trace ...

Arginine fork

Biology; Biochemistry

A specific kind of interaction between an RNA and an RNA-binding protein in which the two equivalent guanidinium nitrogens of an arginine residue interact with adjacent phosphates of a ...

SOS repair

Biology; Biochemistry

An error-prone DNA repair process induced in response to ultraviolet-light-induced mutagenesis. In the face of pyrimidine dimerization, it allows for continued DNA resynthesis with relaxation of the ...