Molecular biology

Molecular biology

Contributors in Molecular biology

Molecular biology

A mobile genetic element composed of repetitive DNA sequences that flank open reading frames, including one that codes for a reverse transcriptase. In contrast to transposons, which in prokaryotes ...

Signal recognition particle (SRP)

Biology; Biochemistry

In the synthesis of secretory, endoplasmic reticulum (ER), Golgi apparatus, lysosomal and integral membrane proteins, a ribonucleoprotein that recognises a signal sequence and prevents further ...

Molecular ruler

Biology; Biochemistry

A method for measurement of distances on a molecular scale; the estimation of distances between a fluorescence energy donor and receptor, evaluated from the efficiency of resonance energy transfer, ...

Representation

Biology; Biochemistry

A portion of the genome with lowered complexity (e.g. by cleavage with an infrequent cutting restriction nuclease, ligated to oligonucleotide adapters so it can then be amplified by PCR), but that ...

Death-associated protein (DAP)

Biology; Biochemistry

A protein that induces apoptosis. It binds to a death receptor on the plasma membrane, resulting in an intracellular cascade of events that acitivates caspases and eventually causes apoptosis.

Side shelf experiment

Biology; Biochemistry

An experimental approach to discovery of a metabolic precursor or regulator, in which candidates for activity are randomly selected according to availability rather than by intelligent design.

Normalised cDNA library

Biology; Biochemistry

A library that includes all cDNA clones at approximately equal frequencies, unlike most cDNA libraries, which represent cDNAs in rough proportion to the occurrence of their mRNA in the source.