The process by which a biological structure, especially a relatively simple structure, is formed by a sequence of enzymic reactions that starts from common metabolites or 'synthons', e.g. the synthesis of haem from glycine and succinyl-CoA; the synthesis of steroids from acetyl-CoA. For the assembly of larger structures, such as membranes, via non-covalent interactions, the term synkinesis has been coined, with the subunits being termed synkinons.