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Caspase-12

A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 12 is activated by pro-apoptotic factors that are released during cell stress and by CARD signalling adaptor proteins. It activates apoptosis by cleaving and activating effector caspases.

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  • Part of Speech: noun
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  • Industry/Domain: Medical
  • Category: Medicine
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