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Tricarboxylic acid cycle (TCA cycle)
The metabolic pathway in which acetyl-CoA is catalytically oxidised to carbon dioxide, with the concomitant reduction of NAD+ and FAD via a series of tricarboxylic (citric, cisaconitic and isocitric) and dicarboxylic (succinic, fumaric, malic and oxaloacetic) acids. The actual carbon atoms that appear as CO2 after a single passage through the cycle are not identical to those that entered as acetyl-CoA. Also known as the citric acid cycle or the Krebs cycle.
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