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Molecular biology
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Molecular biology
Cysteine switch
Biology; Biochemistry
An activation mechanism for matrix metalloproteinase family zymogens (named in reference to the zipper-type mechanism), in which the thiol group of a cysteine residue in the N-terminal propart binds ...
Velcro mechanism
Biology; Biochemistry
An activation mechanism for matrix metalloproteinase family zymogens (named in reference to the zipper-type mechanism), in which the thiol group of a cysteine residue in the N-terminal propart binds ...
Random peptide library
Biology; Biochemistry
For purposes of identification of polypeptides that have a high affinity for a target structure, the assortment of, e.g., the 520 to 720 penta- to hepta-peptides that may be incorporated into a phage ...
Monoclonal antibody (mAb)
Biology; Biochemistry
An immunoglobulin preparation that is completely homogeneous, due to its formation by daughters of a single progenitor cell that has been programmed for the synthesis and secretion of one specific ...
Epitope
Biology; Biochemistry
The antigenic determinant; i.e. that part of an antigen to which an antibody is directed; it defines the specificity of the antigen and consequently binds to the receptor on a T-cell or to the ...
DNA fingerprinting
Biology; Biochemistry
A method to generate a pattern of DNA restriction fragments that is unique to an individual, especially for forensic purposes. DNA from blood, semen or another tissue sample is isolated and cleaved ...