Molecular biology

Molecular biology

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Molecular biology

Heterogeneous

Biology; Biochemistry

Descriptive of a diversity according to some criterion for detecting it; e.g. a mixture of proteins or polynucleotides of differing electrophoretic mobility, size or sequence. Heterogeneity is ...

The site of interaction between two double-stranded DNA molecules; at regions where the two double strands are homologous, equivalent strands of each duplex break and exchange complementary strands ...

Illegitimate recombination

Biology; Biochemistry

Recombination with non-homologous regions of DNA. Each of the polynucleotide strands of double-stranded DNA is religated with DNA from different regions of the same or different chromosomes.

Heterogenous

Biology; Biochemistry

Descriptive of a phenotype which is expressed by two or more genotypes, in contrast with polygeneous, which is descriptive of a phenotype which requires several genes together for its expression.

Ligase chain reaction (LCR)

Biology; Biochemistry

A technique for detection and amplification of target DNA sequences. Two oligodeoxynucleotides are synthesised which between them are complementary to the entire target sequence, one to the 5'-side ...

Positional cloning (reverse genetics)

Biology; Biochemistry

The search for a gene (e.g. that for cystic fibrosis) with no knowledge of the gene product by locating it on the basis of linkage analysis with other genetic traits or individual polymorphisms in ...

Fourier transformation

Biology; Biochemistry

An analysis based on Fourier's theorem that any periodic function may be reduced to a series of sine and cosine terms, each represented by an amplitude and a phase. The transformation is the casting ...