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Molecular biology
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Molecular biology
Vaccinome
Biology; Biochemistry
A plasmid that contains a DNA sequence which encodes an immunologically effective protein, such as an HLA T-cell epitope. A string-of-beads vaccine plasmid is a vaccinome that contains many such ...
Chemotaxis
Biology; Biochemistry
The movement of a cell along the concentration gradient of a chemical, the chemotactic agent, toward its source, in the case of the chemical being a chemoattractant, or away, in the case of a ...
Homomeric
Biology; Biochemistry
Descriptive of a complex of a single kind of subunit, e.g. bacterial glutamine synthetase; contrasted with heteromeric, which is descriptive of a complex of two or more kinds of subunit, e.g. ...
Chargaff's rule
Biology; Biochemistry
An empirical finding that in DNA the frequency of A equals the frequency of T, and the frequency of G equals the frequency of C; later given a theoretical basis by the Watson-Crick double-helix model ...
Glycoprotein hormone
Biology; Biochemistry
A representative of a class of hormones that share nearly identical A-chains and unique B-chains, each with about 125 amino acid residues and N-linked or O-linked carbohydrate moieties, e.g. ...
HTF island
Biology; Biochemistry
A tiny fragment, 1000-2000bp long, generated by action of the restriction nuclease HpaII; usually found associated with expressed genes; characterised by the relatively rare CpG dinucleotide that ...
Homologous replacement
Biology; Biochemistry
A method to alter a cell's genome by introduction of a vector into the nucleus of a targeted germ or somatic cell, where it can pair with the cognate sequence of the chromosomal DNA and replace the ...