Molecular biology

Molecular biology

Contributors in Molecular biology

Molecular biology

The likelihood of finding an amino acid residue in a certain secondary structure, e.g. glycine in an α-helix. Data from statistical surveys, host-guest analysis, model peptides, directed mutagenesis ...

Inner philtre effect

Biology; Biochemistry

A fluorescence spectroscopy phenomenon; the decrease in fluorescence emission seen in concentrated solutions due to the absorption of exciting light by the fluorophore that is close to the incident ...

Interphase nucleus mapping

Biology; Biochemistry

A variant of the usual fluorescence in situ hybridization technique in which non-mitosing cells are used to visualise a genetic marker on a (non-visible) chromosome by use of a fluorescence-labelled ...

Anchored reference marker

Biology; Biochemistry

One of many genes that are used in mapping of chromosomes. Having a well defined locus within a chromosome, it is used to test for genetic linkage in order to localise new traits; also, in ...

Diauxie

Biology; Biochemistry

Bacterial growth in two stages which occurs when the bacteria are grown on two carbon sources, e.g. glucose and xylose. The first phase corresponds to consumption of one compound, followed by a lag ...

Mediator

Biology; Biochemistry

A complex of proteins that allows initiation of cell- and/or cell cycle-specific control of eukaryotic transcription. The complex bridges a (usually) upstream promoter DNA sequence bound to an ...

Zymogen

Biology; Biochemistry

A proenzyme; an inactive precursor of an enzyme, e.g. trypsiongen. Often, the zymogen is proteolytically activated by an endonuclease. In the case of some aspartate proteases, an acid-catalyzed ...