Molecular biology glossaries and terms

Fresco-Alberts-Doty model

Biology; Biochemistry

A region in a single polynucleotide strand containing adjacent complementary sequences that allows the polynucleotide to fold back upon itself and form a double-stranded section, as in the cloverleaf ...

Ataxia telangiectasia mutated

Biology; Biochemistry

Ataxia telangiectasia mutated (ATM) is a protein kinase enzyme that phosphorylates regions of chromatin in DNA following double-stranded breaks (DSBs). Mutations in ATM cause the neurodegenerative ...

Single-molecule

Biology; Biochemistry

Descriptive of the enzyme kinetics, or more generally the dynamics of molecules such as enzymes, ion chanels, molecular motors, etc. studied in isolation (e.g. by atomic force or fluorescence ...

Hairpin loop

Biology; Biochemistry

A region in a single polynucleotide strand containing adjacent complementary sequences that allows the polynucleotide to fold back upon itself and form a double-stranded section, as in the cloverleaf ...

Aspartate-glutamate carrier

Biology; Biochemistry

A carrier protein of the mitochondrial inner membrane that catalyses the exchange of the amino acids glutamic acid and aspartic acid across the inner membrane. This activity is an important part of ...

Autoradiography

Biology; Biochemistry

A technique for visualisation of radioactivity in histological preparations, paper chromatograms or slab gels from electrophoresis by overlaying the surface with X-ray film and allowing the radiation ...

Aggresome

Biology; Biochemistry

A cytological inclusion in cells that is composed of damaged or mis-folded protein molecules, often following heat stress. Presumably amount of protein in an aggresome is too large to be handled by ...

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