Molecular biology

Molecular biology

Contributors in Molecular biology

Molecular biology

The synthesis of multiple copies of a specific gene, which remain as tandem repeats within the chromosome or are segregated as satellite DNA. Amplification is usually not inherited, in contrast to ...

Paradigm

Biology; Biochemistry

In science, a key example that represents and illustrates a range of related cases; e.g. Lac as a paradigm of bacterial operons. The word is also used as a synonym for model, such as a knock-out or ...

Candidate

Biology; Biochemistry

A compound, metabolite or peptide, etc. with a putative role; e.g. a candidate hormone may be a natural peptide which has in vitro bioactivity, but for which its characteristics in vivo have not yet ...

Peptide bond

Biology; Biochemistry

The amide bond formed by condensation of the α-carboxy group of one amino acid with the α-amino group of another; the bond that joins together the amino acid residues that comprise a protein, peptide ...

Optode

Biology; Biochemistry

A biosensor with a light-detecting sensor, e.g. a device that detects the lowering of pH due to the action of glucose oxidase at the end of a fibre optical light guide by the effect on a pH-sensitive ...

Acyl-enzyme

Biology; Biochemistry

An intermediate in the hydrolysis of substrates by some peptidases and esterases, e.g. by serine proteinases, in which the acyl moiety of the substrate is transiently attached to a serine hydroxy ...

Multiplex fluoresence in situ hybridization (multiplex FISH)

Biology; Biochemistry

A method involving the use of several fluorophore-tagged oligonucleotides to simultaneously label metaphase chromosomes, and their discrimination and visualisation through the use of narrow band ...