Molecular biology

Molecular biology

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Molecular biology

Receptor

Biology; Biochemistry

The binding site for a hormone or neurotransmitter that initiates its action at the cellular level. First proposed about a century ago to fulfil the postulate that agents may act only if they can ...

A technique to prepare cells for scanning electron microscopy; cleavage of a solidly frozen cell, followed by freeze-etching, i.e. sublimation of some of the frozen water of the cell and coating the ...

Amplification

Biology; Biochemistry

The causation of a quantitatively major biochemical or physiological event by a quantitatively minor initiator, e.g. the blood clotting cascade, ion gating; also, using the polymerase chain reaction, ...

Ab initio

Biology; Biochemistry

From the beginning, as opposed to pre-existing, e.g. and ab initio complex is one that is assembled from its completely separated subunits, or an ab initio calculation is one that is constructed from ...

Glycation

Biology; Biochemistry

The reversible condensation of the carbonyl group of a sugar with an amino group of a protein to form a Schiff base that often triggers subsequent irreversible rearrangements, e.g. the condensation ...

Fragment reaction assay

Biology; Biochemistry

A measure of the transferase phase of protein synthesis independent of mRNA and many ribosomal factors; i.e. the transfer of an amino acid from its position esterified to the 3'-end of a tRNA (or ...

Membrane protein secretase

Biology; Biochemistry

A sheddase, a matrix metalloprotease that cleaves an exposed non-globular region (the stalk) of a protein attached to the outer surface of the plasma membrane, often a transmembrane protein, to ...