Molecular biology

Molecular biology

Contributors in Molecular biology

Molecular biology

A partial enzymic reaction, especially when only one of two substrates is present, in which chemical groups or single atoms of the substrate equilibrate with the medium, with a cofactor or with one ...

Transmembrane domain

Biology; Biochemistry

A feature of most intrinsic proteins of plasma or vesicular membranes; a polypeptide sequence of about seven residues if β-sheet, up to 22 residues if α-helix, that connects extracellular to ...

Leucine scissors

Biology; Biochemistry

A supersecondary structure of some DNA-binding proteins; a coiled coil of two parallel -helices. Each is of about 30 residues in length and contains leucine residues at every seventh position, which ...

Peptoid

Biology; Biochemistry

An analogue of a polypeptide, a poly-glycine in which the backbone nitrogen atoms are substituted with groups the same as or different from those of natural amino acids. Although these polymers do ...

Functional divergence ratio (FDR)

Biology; Biochemistry

A measure of the evolutionary selective pressure on a protein. In a family of homologous proteins, or the genes encoding them, the amino acid residues are categorised as functional (e.g. those at the ...

Sandwich immunoassay

Biology; Biochemistry

A method for quantification of an antigen large enough to have two epitopes. The antigen serves as a bridge between an immobilised (captive) antibody attached to one epitope, and a radioisotope-, ...

Thioredoxin

Biology; Biochemistry

This is a small redox-active protein with an exposed dithiol motif (-CXXC-) that cycles between a disulphide and a dithiol. The dithiol reduced form is an important cofactor in a number of biological ...