Molecular biology

Molecular biology

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Molecular biology

Charge relay system

Biology; Biochemistry

A tautomeric form of a protein in which a formal charge on one dissociating group is moved to another in the same protein. In serine proteinases, for example, an internal Ã- (sometimes a αγ-) ...

A technique for visualising subcellular structures at very high resolution (near 2.5 nm). The material is prepared for electron microscopy; electron micrographs are taken as the sample is tilted + or ...

Nucleomorph

Biology; Biochemistry

A cellular inclusion, bound by multiple membranes, that contains a small amount (ca. 500 kbp) of genomic DNA. These inclusions are thought to be the products of secondary endosymbiosis, e.g. in an ...

Countercurrent distribution

Biology; Biochemistry

A method for separation of compounds based on differing partition ratios between immiscible liquids. In a linear series of many units (each consisting of an upper and a lower phase) after ...

Chromosome walking

Biology; Biochemistry

A strategy for mapping and sequencing a chromosome. Large restriction fragments are generated and, by Southern blotting with an RNA or cDNA probe, a single starting point is identified. New probes ...

Zonation

Biology; Biochemistry

The phenomenon by which specific areas of an organ have characteristic metabolic functions; e.g. alanine aminotransferase activity is relatively high in the cells of the liver served by the portal ...

Cytochrome c

Biology; Biochemistry

A haem protein that is present in the mitochondrial intermembrane space. Its primary function is to act as a single electron relay between respiratory complexes in the respiratory chain, carrying ...