Molecular biology

Molecular biology

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Molecular biology

Translocation

Biology; Biochemistry

In genetics, the movement of a portion of one chromosome to another; in protein synthesis, the transfer of the newly elongated peptidyl-tRNA from the amino acyl site to the peptide site of a ...

A large family of integral membrane proteins with seven transmembrane helical domains; on the extracellular surface they bind activating ligands, which induce conformational changes through to the ...

Satellite DNA

Biology; Biochemistry

Short repetitive DNA sequences that occur mainly at the ends or in the centre of chromosomes and are therefore suspected of serving structural roles; also, polynucleotides that are separable, on the ...

Spliceosome

Biology; Biochemistry

A complex of (small nuclear RNA)-protein complexes and other proteins that assemble on a pre-mRNA and catalyse the excision of an intron in a process mechanistically similar to group II ...

Lepore haemoglobin

Biology; Biochemistry

A class of haemoglobin in which there has been a faulty crossing-over between the adjacent genes for β- and δ-globins, producing a globin with the N-terminus of δ-globin and the C-terminus of ...

Multivesicular body (MVB)

Biology; Biochemistry

A subcellular structure that travels between the inside surface of the plasma membrane and endosomes, perhaps along a tubular endocytotic network. It scavenges endocytosed receptors destined for ...

Hypoacetylaspartia

Biology; Biochemistry

Hypoacetylaspartia is due to a deficiency of the enzyme N-acetyltransferase (NAT). NAT catalyses the formation of N-acetylaspartate (NAA) from aspartate and acetyl-CoA. NAA is a brain-specific ...