Molecular biology

Molecular biology

Contributors in Molecular biology

Molecular biology

A gene that is coupled with a gene of primary interest when they are inserted together into a cell. The reporter gene allows identification of those few cells that have been successfully transformed ...

Deletion mapping

Biology; Biochemistry

The assignment of the relative positions of deletion mutations along chromosomes. In the first phase, many individuals are studies for the presence of cytogenetic markers and later phases use ...

Antisense

Biology; Biochemistry

Descriptive of an endogenous or semi-synthetically produced oligoribonucleotide complementary to mRNA and capable of base-pairing and annealing with mRNA to prevent translation; or of an ...

AT queue

Biology; Biochemistry

A model that accounts for chromosomal banding. The microscopic appearance of chromosomes during mitosis (metaphase) displays chromomeres and interchromomeres, i.e. G bands (Giemsa stain) and R bands ...

Headward

Biology; Biochemistry

Descriptive of a mechanism of polymerization. The head of a biosynthetic monomer is defined as the chemically activated site (i.e. the carbonyl groups of amino acyl-tRNA or fatty acyl-CoA esters, the ...

Massively parallel signature sequencing (MPSS)

Biology; Biochemistry

A method for automated identification by sequence and quantitative evaluation of expressed genes, which is unaffected by sequence-dependent variations in hybridization efficiencies. A microbead cDNA ...

Bidirectional PCR amplification of specific alleles (bi-PASA)

Biology; Biochemistry

A method for determination of zygosity. Two sets of primers are used. Of the inner set, primer A is complementary to a point mutation on the coding strand and primer B is complementary to the ...