Molecular biology

Molecular biology

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Molecular biology

Amino acid

Biology; Biochemistry

Usually an α-amino acid, in which a carboxy and an amino (or imino) group are attached to the α-carbon; triple- and single-letter codes are shown: alanine Ala A arginine Arg R asparagine ...

The activity of the precursor of mature RNA whereby it catalyses its own (cis>) splicing. Group I introns (examples are Tetrahymena rRNA and hammerhead ribozymes) are self-spliced with the assistance ...

Mismatch repair analysis

Biology; Biochemistry

An assay system for detection of single-base mismatches in a DNA fragment of up to 10 Kb in length, which depends upon an Escherichia coli repair system that detects mismatched bases between a newly ...

Oncogene

Biology; Biochemistry

A gene present in normal cells which when altered can transform the normal cell into a malignant cell. (When emphasising this relationship, the unaltered gene is called a proto-oncogene and the ...

Ligand-mediated PCR (LMPCR)

Biology; Biochemistry

A method for amplification of a DNA fragment or a series of fragments with a single known primer-binding site. The fragment is denatured and hybridised with the primer. Extension of the primer with a ...

Kininogen

Biology; Biochemistry

A protein that contains the sequence Arg-Pro-Pro-Gly-Phe-Ser-Pro-Arg which has inhibitory activity against cysteine proteinases. A kininogen is a precursor of a kinin, which is a decapeptide or ...

Watson-Crick model

Biology; Biochemistry

The arrangement in space of two polynucleotide chains in which each chain is wrapped around the other to form two antiparallel spirals. Each strand presents to the other the bases, purine to ...