Molecular biology

Molecular biology

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Molecular biology

Lysosomal storage disease

Biology; Biochemistry

A hereditary deficiency of one of the lysosomal enzymes involved in turnover of cellular components. An inability to degrade a substance often leads to the engorgement of the lysosomes with the ...

Muscle that on microscopic examination shows a banding pattern that is due to the regular spacing of areas of overlap of thick and thin filaments within each sarcomere; includes skeletal muscle and ...

Gatekeeper protein

Biology; Biochemistry

A protein that monitors transfer of a protein from the endoplasmic reticulum to the Golgi apparatus and prevents transfer of newly synthesised proteins with inappropriate conformations or with ...

Amphitropic

Biology; Biochemistry

Having an affinity for both lipid and aqueous environments, e.g. a membrane-associated protein that has domains that are embedded in the membrane and others that extend into the cytoplasm or the ...

Fatty acid

Biology; Biochemistry

A carboxy group on an alkyl chain that is usually unbranched; may be a short-chain (alkyl group contains less than 7 carbons), medium-chain or long-chain (alkyl group contains more than about 11 ...

Ferric chloride test

Biology; Biochemistry

The chelation of Fe 3+ by an a-oxo acid to give a coloured product, as a test for metabolic products of amino acids, e.g. with α-oxophenylpyruvate as an indirect test for excess levels of ...

Molecular organelle

Biology; Biochemistry

A very large, non-membrane-limited aggregate of subunits that in prokaryotes functions like an organelle. They occur also in eukaryotes, e.g. the proteasome, which as a 26 S multimer is a cylinder 40 ...