Molecular biology

Molecular biology

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Molecular biology

Transcytosis

Biology; Biochemistry

The transport of materials across a polarised cell, e.g. in digestion from the apical surface of a cell of the intestinal epithelium and its movement across the cell to the basolateral surface.

Quenching

Biology; Biochemistry

In fluorescence spectroscopy, a decrease in emission due to a variety of causes that dissipate energy of the excited state, e.g. transfer of energy to a non-fluorescent molecule such as molecular ...

One-gene one-enzyme hypothesis

The proposal that arose from genetic studies on the effects on amino acid metabolism of mutations in Neurospora, that there is a one-to-one correspondence between enzymes and the genes that encode ...

Transgenic

Biology; Biochemistry

Descriptive of an animal that has developed in a surrogate mother from a fertilised ovum that had been injected with a recombinant DNA gene; contrasted with congenic, meaning of the same genetic ...

Concatenate

Biology; Biochemistry

A structure formed by two or more interlinked closed circular (cc)DNAs; formation occurs between the rapid replication of a ccDNA and the slow nicking of one of the ccDNAs to release it from the ...

Permeability coefficient

Biology; Biochemistry

A quantitative measure of the rate at which a molecule can cross a membrane such as a lipid bilayer; expressed in units of cm/s and equal to the diffusion coefficient divided by the width of the ...

Catenane

Biology; Biochemistry

A structure formed by two or more interlinked closed circular (cc)DNAs; formation occurs between the rapid replication of a ccDNA and the slow nicking of one of the ccDNAs to release it from the ...