Molecular biology

Molecular biology

Contributors in Molecular biology

Molecular biology

The Michaelis constant as observed under conditions (e.g. the presence of a competitive inhibitor) that would hinder the determination of its true value; in the case of a two-substrate enzyme, the ...

Sigmoidal

Biology; Biochemistry

S-shaped; descriptive of the appearance of a graph that shows dependence of rate on substrate concentration for a multimeric enzyme that is accelerated by binding of more than one substrate molecule; ...

Superinduction

Biology; Biochemistry

The additional increase in the rate of synthesis of a protein caused by interference with the cellular apparatus for protein or mRNA synthesis that follows an increase in transcription of the gene. ...

Multiple-copy single-strand DNA (msDNA)

Biology; Biochemistry

A satellite DNA detected in some bacteria that features an oligoribonucleotide attached by the 2'-hydroxy group of an internal guanylate residue to the 5'-end of an oligodeoxyribonucleotide, while ...

Biomolecular interaction analysis (BIA)

Biology; Biochemistry

The detection by a biosensor of a specific binding event for quantification of the ligand. One kind of BIA is surface plasmon resonance, the observation of polarisation of light reflected from a ...

Two-component pathway

Biology; Biochemistry

A pattern of molecular organisation by which responses to external stimuli are processed by cells to effect modulation of output, such as chemotaxis in bacteria, or osmolarity regulation in plant ...

Mutator phenotype hypothesis

Biology; Biochemistry

A proposal for the mechanism of cancer, based the fact that mutations are relatively much more common in cancer cells than in normal cells, and even increase as a tumour grows. An initial mutation, ...