Molecular biology

Molecular biology

Industry: Biology

Add a new term

Contributors in Molecular biology

Become a Contributors

Molecular biology

Double-strand-break repair model

Biology; Biochemistry

Double-strand-break repair model A mechanism proposed for the repair of DNA that has been fragmented at in a non-homologous region. The strands are unwound at the two ends to expose a site of ...

Metal-binding finger

Biology; Biochemistry

A motif of which seven or more may appear in a DNA-binding protein. Each is characterised by two closely spaced cysteine and two histidine residues that serve as ligands for a single Zn 2+ . When ...

Zinc finger

Biology; Biochemistry

A motif of which seven or more may appear in a DNA-binding protein. Each is characterised by two closely spaced cysteine and two histidine residues that serve as ligands for a single Zn 2+ . When ...

Subtractive hybridization

Biology; Biochemistry

A variation of subtractive DNA cloning in which the restriction-nuclease-cleaved tester DNA is biotinylated before annealing with an excess of randomly sheared driver DNA. Annealing is halted at ...

An experimental approach to identification of the gene responsible for a given enzymic activity. Each open reading frame (ORF) of an organism, yeast for instance, is fused to the cDNA of glutathione ...

Diagonal electrophoresis

Biology; Biochemistry

A method for identification of a particular kind of peptide in a mixture by identical electrophoretic steps, the second at a 908 angle to the first, with a chemical modification introduced between ...

Insulator

Biology; Biochemistry

A DNA sequence that contributes to limitation of chromatin activation to distinct segments. In the domain boundary model, the insulator putatively binds nucleoprotein complexes along the chromatin ...