21 Terms
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Biochemistry
The scientific study of the chemistry of living matter.
Industry: Biology; Biotechnology
Add a new termContributors in Biochemistry
Biochemistry
Self-sustained sequence replication (3SR)
Biology; Biochemistry
A technique for amplification of a DNA sequence, based on the steps of retroviral replication of nucleic acids. Beginning with a clean DNA sequence, DNA-dependent RNA polymerase makes a RNA ...
Affinity cleavage
Biology; Biochemistry
A variation of the footprinting technique in which a DNA molecule is cleaved at a site occupied by a binding protein. A metal chelator (e.g. ethylenediaminetetra-acetate (EDTA)) is covalently ...
Innate immunity
Biology; Biochemistry
A system of blood factors, especially the complement system, and cells, especially macrophages, which affords protection against invading micro-organisms. Unlike acquired or adaptive immunity, which ...
Induced-fit theory
Biology; Biochemistry
A model for interaction of a protein with a ligand in which the protein binds preferentially with one of several conformers of the ligand; especially enzyme action in which the substrate is proposed ...
Nuclear pore complex (NPC)
Biology; Biochemistry
The site on the nuclear membrane through which proteins are transported into, and RNA is transported out of the cell nucleus. The NPC includes proteins that recognise nuclear localization sequences ...
Achilles heel cleavage
Biology; Biochemistry
A method for cleaving of DNA at very specific sequences. The site of cleavage is able to bind a specific protein, e.g. the lac repressor, that already contains a restriction site or is engineered to ...
Rack model
Biology; Biochemistry
A model for interaction of a protein with a ligand in which the protein binds preferentially with one of several conformers of the ligand; especially enzyme action in which the substrate is proposed ...
