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Molecular biology

Contributors in Molecular biology

Molecular biology

Central dogma

Biology; Biochemistry

In biology, the proposition that the permanent repository of genetic information is DNA which can be replicated, and that the information is expressed unidirectionally by transcription into RNA and ...

EF hand

Biology; Biochemistry

The region in some homologous calcium-binding proteins where the ion is located. The E and F helices of calmodulin, troponin C, etc., resemble the extended index finger (E helix) and thumb (F helix) ...

Ferguson plot

Biology; Biochemistry

A graphical representation of electrophoretic mobility as a function of gel concentration, according to the relationship: logM o /logM=K r C, where M o is the free mobility, M is the mobility in ...

Extremophile

Biology; Biochemistry

An organism that can live in an extreme environment, e.g. barophiles (or piezophiles) that live under high pressure, psychrophiles that live at low temperatures, and thermophiles and ...

RNA single-strand conformational polymorphism (rSSCP)

Biology; Biochemistry

A variant of the SSCP technique for detection of mutations in a DNA fragment in which mobility shifts of bands of mutant compared with normal DNA are more pronounced. A phage promoter is added to one ...

Coupled-enzyme assay

Biology; Biochemistry

The determination of a substrate or enzyme activity by coupling of one enzymic reaction with another, more easily detectable, reaction. The product of the first reaction is the substrate for the ...

Sarcomere

Biology; Biochemistry

The minimal functional unit of skeletal muscle; roughly a cylinder bounded on its ends by Z-lines where the thin filaments are anchored; these extend towards the center. Thick filaments extend from ...

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