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Molecular biology
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Molecular biology
Transpeptidation
Biology; Biochemistry
A characteristic of some proteinases; the transfer of one product of the catalytic cleavage to another peptide rather than to water; the transfer of the N-terminal fragment to the amino group of an ...
Surface-enhanced laser desorption/ionization (SELDI)
Biology; Biochemistry
A pre-mass spectroscopy screening and selection technique. Spots on an inert surface are modified to bind a desired types of protein; e.g. with phenyl or amino groups for hydrophobic or acidic ...
Omic research
Biology; Biochemistry
Following the currency of 'genomics', additional words have been coined to denote the compilation of data bases as resources for future research and analysis; proteonomics for proteins, kinomics for ...
Unnatural amino acid mutagenesis
Biology; Biochemistry
A method for replacement of an amino acid residue of a protein with a non-naturally occurring amino acid. The mRNA that encodes the protein is modified to encode a nonsense suppressor codon. For ...
Affinity precipitation
Biology; Biochemistry
A technique for purification of proteins that depends upon reversible attachment to a ligand. A bis-ligand (or homofunctional ligand) is a double-headed molecule that can attach at each end to part ...
Aromatic
Biology; Biochemistry
Descriptive of an organic compound that contains a planar cyclic structure of unusually stability due to the delocalization of electrons. The simplest aromatic compound is benzene, but the family of ...
Substrate phage
Biology; Biochemistry
A method for identification of the substrate specificity of a proteinase by its ability to select a phage that expresses a cleaveable polypeptide, which is one of a library of random amino acid ...
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