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Molecular biology

Contributors in Molecular biology

Molecular biology

Gortner and Grendel model

Biology; Biochemistry

A model in which erythrocyte membranes comprise only phosphoacylglycerols, i.e. no protein or sterol component is envisaged; the model presents a bilayer in which each leaflet is composed of lipids ...

Fluorescence-activated cell sorting (FACS)

Biology; Biochemistry

A technique for separation of cells according to their fluorescence after attachment of a fluorophore to specific cells, e.g. with a fluorescent antibody. Droplets that contain no more than one cell ...

Phase problem

Biology; Biochemistry

In X-ray crystallography, the gap between the requirements for reconstruction of a model - for each reflection (defined by the angle of its diffraction), the amplitude (related to intensity) and ...

Variable number tandem repeat (VNTR)

Biology; Biochemistry

A minisatellite DNA; the repetition of a 35-80bp sequence, to a size of up to 2kbp, that is characteristic of an individual. VNTRs are used in forensic science to identify, or exclude, suspects of a ...

Molecular model

Biology; Biochemistry

A physical representation, e.g. balls and sticks, used to represent the structure of a compound or macromolecule, or a computer graphics simulation of such a structure. More sophisticated versions ...

Rapid amplification of cDNA ends (RACE)

Biology; Biochemistry

A PCR-based method to obtain cDNA clones of rare transcripts which begin with only a partial internal sequence. The 3'- and 5'-ends are analysed separately; a single (-)-strand is first constructed ...

Activation energy

Biology; Biochemistry

The energy needed to raise the reactants, or an enzyme-substrate complex, to the transition state, where it has an equal likelihood of conversion to product or reversion to reactants. This value is ...

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