Biochemistry

Biochemistry

The scientific study of the chemistry of living matter.

Industry: Biology; Biotechnology

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Biochemistry

Biomolecular interaction analysis (BIA)

Biology; Biochemistry

The detection by a biosensor of a specific binding event for quantification of the ligand. One kind of BIA is surface plasmon resonance, the observation of polarisation of light reflected from a ...

Two-component pathway

Biology; Biochemistry

A pattern of molecular organisation by which responses to external stimuli are processed by cells to effect modulation of output, such as chemotaxis in bacteria, or osmolarity regulation in plant ...

A proposal for the mechanism of cancer, based the fact that mutations are relatively much more common in cancer cells than in normal cells, and even increase as a tumour grows. An initial mutation, ...

Superoxide dismutase

Biology; Biochemistry

Enzymes that catalyse the dismutation of superoxide to hydrogen peroxide through the use of a redox active metal cofactor such as a copper or a manganese. In mammals there is a cytosolic isoform ...

Reactive immunisation

Biology; Biochemistry

A technique to widen the scope of catalytic reactions effected by abzymes. Reactive compounds are used as antigens; some of the resulting antibodies are directed to the reaction complex with a ...

Intasome

Biology; Biochemistry

A nucleoprotein complex active in integration of bacteriophage DNA into host DNA. Negatively supercoiled host DNA is forced to cross back over itself at points called nodes, which are sites for ...

Hormone

Biology; Biochemistry

A substance that mediates interactions between non-contiguous cells; classically, a substance produced in minute amounts by an organ (an endocrine organ) in one part of the body and transported by ...