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Molecular biology

Contributors in Molecular biology

Molecular biology

Energy balance

Biology; Biochemistry

The thermodynamic necessity that for any organism, the energy intake (nutrients, light for photosynthesis, etc.) must equal the internal heat produced, the work (movement, transport, etc.) and growth ...

Immunofluorescence

Biology; Biochemistry

The visualisation of an antigen in a histological section or on a polyacrylamide slab by allowing it to combine with a fluorophore-tagged antibody. In indirect immunofluorescence the antibody is not ...

Transduction

Biology; Biochemistry

The conversion of one kind of energy into another, e.g. conversion of the chemical energy of ATP into mechanical energy by muscle contraction; also conversion of a signal as it crosses a barrier, ...

Scaffold protein

Biology; Biochemistry

One of the non-enzymic components of a multi- protein signal transduction complex. The complex is assembled upon activation of the receptor or is assembled but dormant until receptor activation. The ...

Cyclophilin

Biology; Biochemistry

An enzyme that binds the immunosuppressant compound cyclosporin, thereby blocking its activity as a peptidylprolyl cis¿trans isomerase. Cyclophilin A is present in the cytosol and when bound to ...

Protein nucleic acid (PNA)

Biology; Biochemistry

A polyamide backbone, e.g. (-NH-CH 2 -CH 2 -NR-CH 2 -CO-) n , which bears purine and pyrimidine bases (R in the formulation) and can mimic oligonucleotides by hybridising with ssDNA or RNA. Some PNAs ...

Surface plasmon resonance (SPR)

Biology; Biochemistry

An optical technique for the detection and quantification of binding which has been incorporated into some biosensors. The material to which binding will be detected is immobilised on the surface of ...

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