Biochemistry

Biochemistry

The scientific study of the chemistry of living matter.

Contributors in Biochemistry

Biochemistry

The moiety of an amino acid residue in a protein, or of a free amino acid, that is attached to the α-carbon and is unique to each amino acid, e.g. the isopropyl group of valine, the benzyl group of ...

Potentiometric titration

Biology; Biochemistry

The use of a potentiometer, especially a pH meter, to follow the titration of an oxidizable group with a reductant (or vice versa) to generate a graph of reduction potential against percentage ...

Respiration state

Biology; Biochemistry

The condition of tightly coupled mitochondria that is characterised by their respiratory rate (all but state 3 are slow) and defined by the rate-limiting component: state 1, ADP- and ...

Hydroxylamine and osmium tetroxide (HOT) technique (chemical mismatch detection)

Biology; Biochemistry

A method for detection of single base substitutions in DNA fragments. Heteroduplexes of normal DNA and homologous mutant DNA are generated; the presence of C mismatches allows cleavage with ...

Positional candidate approach

Biology; Biochemistry

A strategy for identification and cloning of a new gene; a combination of functional cloning, in which a property of the protein product (e.g. immunogenicity or liganding) is used to scan a cDNA ...

Actin

Biology; Biochemistry

A protein present in eukaryotic cells, forming actin filaments, which is a major component of the cell's cytoskeleton, the network of relatively rigid structures within a cell that give it shape. ...

Complement system

Biology; Biochemistry

A series of blood proteins that contribute to innate immunity. When triggered by a foreign substance or particle, a cascade of enzymatic activations and reactions results in chemotaxis, activation of ...